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高脂血症是肾病综合征(NS)的突出表现。然而,高脂血症是否会增加冠心病的危险性尚有争论。若然,是否需要降血脂治疗;再者,尚没有在 NS 患者中测定过各种脂蛋白成分。NS 患者有多种脂蛋白异常,但其原因及真正背景尚未明。病人和方法研究对象为 NS 57例,平均年龄44.8(15～81)岁。男37、女20例。肾功能均正常,未经过治疗,并且无其他可引起血脂异常的代谢性疾病。匹配的正常人57名作对照组。对两组的血清脂类和载脂蛋白水平进行测定。此外,并测定了 NS 患者6例的低密度脂蛋白代谢动力学指数,其中3例在患病恢复后再次测定。
Hyperlipidemia is a prominent manifestation of nephrotic syndrome (NS). However, whether hyperlipidemia can increase the risk of coronary heart disease is still controversial. If so, whether the need for lipid-lowering treatment; Moreover, no determination of various lipoprotein components in NS patients. NS patients have a variety of lipoprotein abnormalities, but the reason and the true background is not yet clear. The patients and methods of study were 57 NS patients, with an average age of 44.8 (15 ~ 81) years. Male 37, female 20 cases. Renal function are normal, untreated, and no other metabolic disorders that can cause dyslipidemia. 57 matched normal control group. Serum lipids and apolipoprotein levels were determined in both groups. In addition, LDL-C was measured in six patients with NS and three of them were measured again after recovery.