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目的:探讨崇州地区妇女妊娠期糖代谢异常的相关危险因素,为临床预防和控制提供理论依据。方法:采用病例对照研究,以2011年6月~2014年5月崇州市妇幼保健院围产保健门诊确诊的妊娠期糖代谢异常的100例孕产妇为病例组,以同期在崇州市妇幼保健院进行产前保健和分娩的糖代谢正常及孕周相同的100例孕产妇为对照组。调查并分析两组孕产妇的一般情况、妊娠及行为等情况,分析妊娠期糖代谢异常的相关因素。结果:Logistic回归分析发现糖尿病遗传史(OR=2.398,95%CI为1.042~5.012)、年龄>28岁(OR=1.413,95%CI为1.322~4.352)、体重指数>24(OR=6.543,95%CI为0.782~2.320)、流产史(OR=0.212,95%CI为0.025~2.256)、吸烟史(OR=0.246,95%CI为0.045~3.452)是妊娠期糖代谢异常的危险因素。结论:年龄>28岁,体重指数>24,有糖尿病遗传史、流产史及吸烟史的孕妇应在妊娠早期进行妊娠期糖尿病筛查。
Objective: To explore the related risk factors of abnormal glucose metabolism during pregnancy in Chongzhou area, and to provide a theoretical basis for clinical prevention and control. Methods: A case-control study was conducted in 100 maternal women with abnormal glucose metabolism in pregnancy during the perinatal health clinic of Chongming MCH from June 2011 to May 2014. A case-control study was conducted in Chongzhou MCH Prenatal care and delivery of normal glucose metabolism and gestational age the same 100 cases of pregnant women as control group. Investigation and analysis of two groups of general situation of maternal, pregnancy and behavior, etc., analysis of glucose metabolism in pregnancy-related factors. Results: Logistic regression analysis showed that the genetic history of diabetes (OR = 2.398, 95% CI 1.042-5,012), age> 28 years (OR = 1.413, 95% CI 1.322-4.352) 95% CI was 0.782-2.320). Abortion history (OR = 0.212, 95% CI 0.025 ~ 2.256) and smoking history (OR = 0.246, 95% CI 0.045 ~ 3.452) were risk factors for abnormal glucose metabolism during pregnancy. CONCLUSIONS: Pregnant women aged> 28 years, with body mass index> 24, with a history of diabetes mellitus, miscarriage history and smoking history should be screened for gestational diabetes during early pregnancy.