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反复发作性疱疹性口腔炎(RAS)是累及口腔粘膜的疾病,约20％人罹 RAS。典型症状为界限分明的疼痛、反复性溃疡生成,溃疡部位最常见在颊粘膜,也常累及舌、软颚和咽部。其病因与多种因素有关,如感染、免疫机理、创伤、应激、遗传因素、内分泌变化、食物过敏和全身性疾病。艾滋病毒(HIV)感染者及艾滋病人易并发严重的 RAS,本文报道2例艾滋病患者罹 RAS。治疗 RAS 常用药物如局部使用皮质激素,局部及全身使用抗生素疗效不佳。
Recurrent herpetic stomatitis (RAS) is a disease involving the oral mucosa, and about 20% of people suffer from RAS. Typical symptoms are well-defined pain, recurrent ulcers, ulcers most commonly found in the buccal mucosa, and often involve the tongue, soft palate and pharynx. The etiology is associated with a variety of factors, such as infection, immune mechanisms, trauma, stress, genetic factors, endocrine changes, food allergies, and generalized disease. People living with HIV and people with AIDS are prone to develop severe RAS, and this article reports 2 people who have AIDS who suffer from RAS. Treatment of RAS commonly used drugs such as topical corticosteroids, topical and systemic use of antibiotics poor efficacy.