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1980年3月~1991年2月用灭活卡介苗(简称“死卡”)治疗慢性支气管炎(简称“慢支”)300例(依据全国慢支临床专业会议修订的临床诊断标准诊断),男138例,女162例;3~78岁;病程6个月~46年。方法将过期冻干卡介苗经适当温度和时间灭活后低温保存备用。每支死卡用稀释液1.2ml,充分摇匀稀释,每次皮内注射0.1ml,每月1次,连用6~12月,无效者停用。结果参照慢支疗效判断标准。疗效如下表。数据表明,总有效率为92.3%,低年龄组有效率偏高。讨论死卡治疗慢支机理可能为死卡内含物质刺激机体抗病系统活跃,或(和)各种抗病因子的释放,吞噬细胞增多,活性增强,增加了抗御和清除有害因
From March 1980 to February 1991, 300 cases of chronic bronchitis (referred to as “chronic bronchitis”) were treated with the inactivated BCG vaccine (referred to as “dead card”) (diagnosed according to the clinical diagnostic criteria revised by the National Branch of the Clinical Branch) 138 cases, 162 females; 3 to 78 years of age; duration of 6 months to 46 years. Methods The expired lyophilized BCG was inactivated by appropriate temperature and time and stored at low temperature for later use. Each dead card with a dilution of 1.2ml, shake well and dilute, each intradermal injection of 0.1ml, once a month, once every 6 to 12 months, invalid disabled. Results refer to chronic bronchitis curative effect judgment standard. The efficacy is as follows. The data show that the total effective rate was 92.3%, high efficiency in the low age group. Discussion Dead card treatment of chronic bronchitis mechanism may be dead card containing substances to stimulate the body active disease-resistant system, or (and) the release of a variety of anti-factor, phagocytic cells increased, increased activity, increased defense and removal of harmful factors