患者女,27岁,因反复咳喘3～4年,近10天睹症加剧并伴畏冷、发热、痰稠粘、胸闷而住院治疗。入院诊断。风心伴二尖瓣狭窄,慢支急性发作。即给青霉素80万u日二次肌注及其它对症治疗,病情日渐好转。连续肌注青霉素6天共960万u,于第7天肌注80万u后约2分钟,患者突然神志不清,口唇发绀,肤色苍白,四肢冰冷,小便失禁,即按青霉素过敏给 Female patient, 27 years old, due to repeated cough 3 to 4 years, nearly 10 days witnessed aggravated and with cold, fever, sputum sticky, chest tightness and hospitalization. Admission diagnosis. Wind heart with mitral stenosis, acute exacerbation of chronic bronchitis. That penicillin 800,000 u second intramuscular injection and other symptomatic treatment, the condition getting better. Continuous intramuscular injection of penicillin six days a total of 9600000 u, in the first 7 days after intramuscular 800000 u about 2 minutes, the patient suddenly unconscious, lips cyanosis, pale complexion, extremities cold, incontinence, that is, according to penicillin allergy