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对4例先天性心脏病室间隔缺损伴肺动脉高压患儿用Swan－Ganz导管监测血流动力学的情况下，观察吸入10mg／LNO后肺动脉压力及心输出量等的改变，结果表明，先天性心脏病室间隔缺损合并肺动脉高压患儿吸入低浓度NO气后，平均肺动脉压及肺血管阻力均较基础状态明显降低（P＜0．05），心输出量则较前增高。提示吸入10mg／LNO可明显降低先天性心脏病伴肺动脉高压患儿的肺动脉压力，增加心输出量。
In 4 cases of congenital heart disease ventricular septal defect with pulmonary hypertension in children with Swan-Ganz catheter hemodynamic monitoring cases, the observation of pulmonary arterial pressure and cardiac output 10mg / LNO change, the results show that congenital heart In patients with ventricular septal defect and pulmonary hypertension, inhalation of low concentration of NO gas, mean pulmonary artery pressure and pulmonary vascular resistance were significantly lower than the basic state (P <0.05), cardiac output increased compared with the previous. Tip inhalation of 10mg / LNO can significantly reduce congenital heart disease in children with pulmonary hypertension pulmonary pressure and increase cardiac output.