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BPH所至下尿路症状(LUTS/BPH)的药物治疗在解除患者症状、预防和阻断BPH的发展,有效降低严重并发症和手术疗法风险的效果令人瞩目,已经成为LUTS/BPH的一线治疗选择。近年来磷酸二酯酶-5抑制剂(PDE5-Is)用于治疗LUTS/BPH的研究成果显著,PDE5-Is不论是单独应用,还是与α1肾上腺能受体拮抗剂(α1-ARAs)联合应用,对于缓解LUTS/BPH的效果确切,联合治疗效果更优。本文就PDE5-Is治疗LUTS/BPH的国内外研究进展作一综述。
BPH to lower urinary tract symptoms (LUTS / BPH) drug treatment in relieving symptoms, preventing and blocking the development of BPH, effective in reducing the risk of serious complications and surgical treatment is remarkable, has become the first line of LUTS / BPH Treatment options. In recent years, the research results of phosphodiesterase-5 inhibitor (PDE5-Is) for the treatment of LUTS / BPH are remarkable. PDE5-Is is used alone or in combination with α1-ARA , For the exact effect of relieving LUTS / BPH, combined treatment is better. This article reviews the research progress of PDE5-Is in the treatment of LUTS / BPH at home and abroad.