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硫氧还蛋白还原酶是一种NADPH依赖的包含FAD结构域的二聚体硒酶,属于吡啶核苷酸-二硫化物氧化还原酶家族成员。它和硫氧还蛋白、NADPH共同构成了硫氧还蛋白系统。T rxR有很多生物学功能,与人类某些疾病的发病机制也密切相关。
Thioredoxin reductase is a NADPH-dependent dimer selenium enzyme that contains a FAD domain and belongs to the family of pyridine nucleotide-disulfide oxidoreductases. It and thioredoxin, NADPH together constitute the thioredoxin system. T rxR has many biological functions and is closely related to the pathogenesis of certain human diseases.