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In this paper, the amplification factor (ks ) of peek ground motion with different exceedance probability in class Ⅱ and Ⅲ sites over Shandong Province was estimated by analyzing the seismic response data of soil layers collected from 358 boreholes of class Ⅱ sites and 140 boreholes of class Ⅲ site. From the results, one can conclude that: (1) The scatter plot of ks generally obeys a normal distribution ; (2) ks decreases with the increase of the strength of input ground motion, which is more apparent in Class Ⅲ site than in class lI site; (3) for class Ⅱ site, with the increase of depth of the bedrock interface where ground motion inputs, ks increases gradually until to a stable value when the depth reaches up to approximately 20 meters or larger. Yet, for class Ⅲ site, ks is insensitive to the depth; (4) the average of ks for class Ⅱ site is 1.47, slightly larger than that used in the Seismic Ground Motion Parameters Zonation Map of China ( GB 18306-2001 ). Also, ks in class Ⅱ and Ⅲ sites at different levels of peak ground acceleration over Shandong Province is preliminarily discussed in the paper.