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目的了解2006-2007年广州市海珠区健康人群麻疹抗体水平。方法采用分层随机抽样的方法,采集海珠区各年龄段健康人群的血清,用酶联免疫吸附试验检测麻疹IgG抗体。结果共调查1879人,麻疹IgG抗体阳性的1503人,总阳性率为79.99%。各年龄组之间麻疹IgG抗体阳性率差异有统计学意义(P<0.01),4~5月龄儿童最低,仅为30.43%;≥35岁成人最高,为93.92%。女性麻疹抗体阳性率为82.57%(905/1096),高于男性76.37%(598/783)(P<0.01)。8月龄至17岁人群麻疹疫苗接种率为96.22%(764/794),各年龄组之间的免疫率差异有统计学意义(P<0.01),18岁以上的707人麻疹免疫史不详。结论广州市海珠区健康人群中小于8月龄未接种麻疹疫苗的婴儿月龄越大,抗体阳性率越低;8月龄后疫苗接种率较高,抗体阳性率也高,表明麻疹疫苗接种是提高人群免疫力的主要因素。
Objective To understand the level of measles antibody in healthy population in Haizhu District of Guangzhou City from 2006 to 2007. Methods The stratified random sampling method was used to collect the serum of healthy people of all ages in Haizhu District, and the measles IgG antibody was detected by enzyme-linked immunosorbent assay. Results A total of 1879 people were surveyed, 1503 were measles IgG positive, the total positive rate was 79.99%. The positive rate of measles IgG between the different age groups was statistically significant (P <0.01), the lowest in children aged 4 ~ 5 months, only 30.43%, and the highest was 93.92% in adults> 35 years old. The positive rate of measles antibody in females was 82.57% (905/1096), higher than that in males (59.3%) (598/783) (P <0.01). The measles vaccination rate was 96.22% (764/794) between August and 17 years old. The immunization rate among all age groups was statistically significant (P <0.01). The history of 707 measles immunizations beyond 18 years old was unknown. Conclusion The positive rate of antibody in the infants less than 8 months old who were not immunized with measles vaccine was lower in healthy population in Haizhu District of Guangzhou City. The positive rate of antibody was lower after 8 months of age. The positive rate of antibody was also higher after 8 months of age, indicating that measles vaccination was The main factor to improve the immunity of the population.