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[目的]了解流行性腮腺炎(流腮)的流行特征及临床表现特点,为制定防控措施提供依据。[方法]对2005年6月至2007年6月青岛市传染病医院感染科收治的126例流行性腮腺炎病例资料进行分析。[结果]126例患者中,市区30例,占23.8%;郊区71例,占56.3%。全年各月均有发病。男性86例,女性40例;年龄4~35岁,平均发病年龄13.5岁;以幼儿、中小学生发病为主,共62例,占49.2%。临床表现主要为发热和腮腺肿痛,脑炎和睾丸炎是常见并发症,分别为38和36例。实验室检查白细胞正常88例,升高30例,下降8例。血清淀粉酶升高36例,丙氨酸氨基转移酶升高16例。异常指标多于1周后恢复正常。应用利巴韦林联合痰热清注射液治疗,取得良好疗效,所有患者均治愈出院,平均住院7 d。[结论]流行性腮腺炎发病年龄有后移趋势,建议青年易感者补种疫苗。痰热清注射液是治疗本病的有效药物。
[Objective] To understand the epidemiological characteristics and clinical manifestations of mumps (Mumps) and provide the basis for making prevention and control measures. [Method] The data of 126 cases of mumps admitted from June 2005 to June 2007 in Qingdao Infectious Diseases Hospital Infectious Diseases were analyzed. [Results] Of 126 patients, 30 were in urban area, accounting for 23.8%; 71 in suburban area, accounting for 56.3%. There are incidences throughout the year. There were 86 males and 40 females, aged from 4 to 35 years with an average age of 13.5 years. Of these, 62 were young children and primary and secondary students, accounting for 49.2%. The main clinical manifestations of fever and parotid swelling and pain, encephalitis and orchitis is a common complication, respectively, 38 and 36 cases. Laboratory tests of normal leukocytes in 88 cases, elevated 30 cases, decreased in 8 cases. Elevated serum amylase in 36 cases, alanine aminotransferase increased in 16 cases. Abnormal indicators returned to normal after more than 1 week. Application of ribavirin combined Tanreqing injection treatment, and achieved good results, all patients were cured and discharged, the average hospitalized 7 d. [Conclusion] The age of onset of mumps tends to shift backward. It is suggested that the susceptible people should be vaccinated. Tanreqing injection is an effective drug for the treatment of this disease.