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本文报道二例母患糖尿病的婴儿,出生时呈现严重的呼吸困难,经插管和气管造口术抢救无效,于出生后六小时内死亡。尸检发现气管和声门狭窄、杓状软骨肥大及严重的心脏畸形,如巨大室间隔缺损、肺动脉闭锁等。多数器官均易受糖尿病的影响形成畸变,最常累及的器官包括骨髂、心脏、肾脏和生殖器。Mφlsted-Pedersen等在大量母患糖尿病与非糖尿病母体婴儿的比较资料中,发现糖尿病组的畸形率比对照组大三倍,
This article reports two infants with a mother-to-child diabetes who present with severe dyspnea at birth who are ineffective after intubation and tracheostomy and die within six hours of birth. Autopsy found tracheal and glottis narrow, arytenoid cartilage hypertrophy and severe heart deformity, such as a huge ventricular septal defect, pulmonary atresia. Most organs are susceptible to the effects of diabetes and distortions, the most commonly involved organs including the bony iliac, heart, kidney and genitalia. Mφlsted-Pedersen, etc. In a large number of maternal and non-diabetic maternal diabetes compared with the data found that diabetic group deformity rate three times larger than the control group,