我科于1993年8月～1997年11月应用脉络宁注射液治疗新生儿缺氧缺血性脑病(HIE)36例,效果满意,现报告如下。1 临床资料 依据1989年8月济南会议制定的HIE诊断标准,临床诊断为HIE的患儿59例,随机分为治疗组和对照组,治疗组36例,男23例,女13例;入院时病程<6小时21例,6～24小时8例,>24小时7例;其中轻度9例,中度18例,重度9例。对照组23例,男14例,女9例;其中轻度7例,中度11例,重度5例。治疗组和对照组患儿均为足月儿,其临床表现分 Our department in August 1993 ~ November 1997 application Mailuoning injection of neonatal hypoxic-ischemic encephalopathy (HIE) in 36 cases, the results are satisfactory, are as follows. 1 Clinical data According to the HIE diagnostic criteria developed by the Jinan Conference in August 1989, 59 children with HIE were randomly divided into treatment group and control group. The treatment group consisted of 36 patients, 23 males and 13 females. On admission, Course of disease <6 hours in 21 cases, 6 to 24 hours in 8 cases,> 24 hours in 7 cases; mild in 9 cases, moderate in 18 cases, severe in 9 cases. The control group of 23 patients, 14 males and 9 females; of which 7 were mild, 11 moderate, severe in 5 cases. The treatment group and the control group of children were full-term children, the clinical manifestations