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泻心汤方由大黄、黄芩、黄连组成。实验研究体外抗凝及抗血小板聚集作用。结果显示,单味药黄连及不同组合和全方均有抗血凝作用。以单味黄连及黄连、黄芩组合较好。单味大黄或黄芩不呈抗凝效应,但两者组合时,则呈协同抗凝效应。在三对组合药中,如药物浓度减低(比例不变),则反而呈现促凝效应。在抗血小板聚集中,除了黄芩反有促聚作用外,均有不同程度抑制血小板聚集的作用。
Xiexin Tangfang consists of rhubarb, astragalus and coptis. Experimental study of anticoagulation and antiplatelet aggregation in vitro. The results showed that the single herb Rhizoma Coptidis and various combinations and all have anticoagulant effects. The combination of single-flavored berberine, berberine and yellow peony is better. The single-flavored rhubarb or scutellaria showed no anticoagulant effect, but when the two were combined, they exhibited a synergistic anticoagulation effect. In the three pairs of combination drugs, if the drug concentration is reduced (invariable proportion), the procoagulant effect appears instead. In the anti-platelet aggregation, in addition to the anti-aggregation effect of astragalus, there are different degrees of inhibition of platelet aggregation.