子痫前期是与血管内炎症反应及内皮细胞功能紊乱相关的疾病,正常妊娠中常见的天然免疫反应在子痫前期表现为反应增强。近来发现Toll样蛋白受体(TLR)是天然免疫应答的重要组分,不仅能识别微生物片段,而且还能识别宿主产物,这些都与“损伤细胞”产生有关,所以TLR也被称为传递炎症 Preeclampsia is a disease associated with intravascular inflammatory response and endothelial cell dysfunction. The natural immune response commonly seen in normal pregnancy is manifested as a response enhancement in preeclampsia. Toll-like receptor (TLR) has recently been found to be an important component of the innate immune response that not only identifies microbial fragments but also identifies host products, all of which are associated with the production of “damaged cells,” so TLRs are also known as transmission of inflammation