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１９９６年在河南省３个县随机抽取２～１９岁健康人群１２７８人份血清，进行了百日咳、白喉、破伤风抗体水平监测。百日咳抗体（微量血凝法）阳性（凝集抗体≥１１６０）率为６０．７％（２４３／４１１），达到保护水平（≥１３２０）者占３７．０％（１５２／４１１），抗体几何平均滴度倒数（ＧＭＲＴ）为１１９；白喉抗毒素（间接血凝法）阳性（≥１１６）率为８１．９％（３５３／４３１），ＧＭＲＴ为１０８，抗毒素平均含量（ＡＴＣ）０．１０６ＩＵ／ｍｌ；破伤风抗毒素（间接血凝法）阳性（≥１４）率为７６．８％（３３５／４３６），ＧＭＲＴ为１７，ＡＴＣ为０．０６５１ＩＵ／ｍｌ。虽然１５～１９岁人群白喉、破伤风ＡＴＣ低于其他年龄组，但均在保护水平以上。
In 1996, 1278 serum samples from 2 to 19-year-old healthy people in 3 counties of Henan Province were randomly selected and their pertussis, diphtheria and tetanus antibody levels were monitored. Pertussis antibody (coagulation antibody≥1160) was 60.7% (243/411), and the protective level (≥1320) was 37.0% (152/411). The geometric mean antibody drop (GMRT) was 119; diphtheria antitoxin (indirect hemagglutination) was 81.9% (353/431), GMRT was 108, and the average antitoxin (ATC) was 0.106 IU / ml; Haemotoxin (indirect hemagglutination) was 76.8% (335/436) in positive (≥14), GMRT was 17 and ATC was 0.0651 IU / ml. Although diphtheria and tetanus ATC among 15- to 19-year-olds were lower than other age groups, they were above the level of protection.