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目的探讨乌司他丁联合甲基强的松龙治疗急性吸入性有机氟中毒的临床效果。方法 94例急性吸入性有机氟中毒患者,随机分为对照组和观察组,各47例。对照组给予甲基强的松龙治疗,观察组给予乌司他丁联合甲基强的松龙治疗,对比两组临床疗效。结果观察组甲基强的松龙疗程、肺部渗出吸收时间短于对照组,差异有统计学意义(P<0.05);观察组治愈率高于对照组,差异有统计学意义(P<0.05)。结论对急性吸入性有机氟中毒患者给予乌司他丁与甲基强的松龙联合治疗可迅速缓解患者临床症状,临床应用价值显著。
Objective To investigate the clinical effects of ulinastatin combined with methylprednisolone in the treatment of acute inhaled organic fluorosis. Methods 94 patients with acute inhaled organic fluorosis were randomly divided into control group and observation group, 47 cases in each. The control group was given methylprednisolone treatment. The observation group was given ulinastatin combined with methylprednisolone treatment. The clinical efficacy was compared between the two groups. Results The duration of treatment of methylprednisolone in the observation group was shorter than that in the control group (P <0.05). The cure rate of the observation group was higher than that of the control group (P < 0.05). Conclusions Combination therapy with ulinastatin and methylprednisolone in patients with acute inhaled organic fluorosis can relieve the clinical symptoms in patients with acute fluorosis. The clinical value is obvious.