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丙烯酰胺亚慢性中毒对大白鼠运动神经传导速度的影响,国内尚未见报道,国外虽有过研究,但其评价运动神经传导速度是以坐骨神经为代表。而本实验除坐骨神经外,还结合尾神经传导速度的改变进行综合分析。 方法与材料 (一)实验动物:将Wistar大白鼠体重190～240g9,随机分4组,每组20只,雄雌各半,分笼饲养。 (二)染毒方式:将纯度为99.9％的丙烯酰胺配制成浓度为147.20、110.85及75.50ppm三份水溶液喂饮三个月,对照组饮自来水。 (三)测量仪器:天津劳动卫生研究所
Acrylamide subchronic poisoning on motor nerve conduction velocity in rats, the domestic has not been reported, although abroad have been studied, but its evaluation of motor nerve conduction velocity is represented by the sciatic nerve. In addition to the experimental sciatic nerve, but also combined with changes in the conduction velocity of the tail nerve to conduct a comprehensive analysis. Methods and Materials (1) Experimental animals: Wistar rats weighing 190-240g9 were randomly divided into 4 groups of 20 rats in each group. (B) the way of exposure: The purity of 99.9% of the acrylamide formulated into a concentration of 147.20,110.85 and 75.50ppm three copies of water solution for drinking three months, the control group drinking tap water. (C) measuring instruments: Tianjin Institute of Labor and Health