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碘杂环-72能提高哇巴因诱发豚鼠心律失常的用量;防治氯化钡、氯化钙导致的心律失常;对结扎冠脉诱发大鼠心律失常有明显预防作用;亦可降低氯仿引起小鼠室颤的发生率,并明显减慢麻醉大鼠的心率。碘杂环-72可能是通过钙拮抗效应而产生抗心律失常作用.
Iodine-72 can increase ouabain-induced guinea pig arrhythmia dosage; prevention and treatment of barium chloride, calcium chloride induced arrhythmia; ligation of coronary arrhythmia rat induced significantly prevent; can also reduce the chloroform caused small Rat ventricular fibrillation incidence, and significantly slow down the heart rate of anesthetized rats. Iodohepta-72 may be anti-arrhythmic by calcium antagonistic effect.