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乙胺碘呋酮为一含碘的苯呋喃衍生物,1962年以来广泛用于心绞痛和心律失常的治疗.已知其副作用可涉及眼(角膜沉着)、皮肤(光敏和色素沉着)、甲状腺(机能亢进或减退)、神经-肌肉、肾和肺(纤维化)等.1981年以来出现对肝脏毒性作用的报导,其中多数为轻度肝功能改变,少数报导发生急性或慢性肝病.单项高转氨酶血症在用药后不久发生,具有许多其他药物引起高转氨酶血症的特点:1.较多见,约占用药患者的11～55%;2.皆为轻度肝功能改变,谷
Amiodarone is an iodinated benzofuran derivative widely used in the treatment of angina pectoris and arrhythmia since 1962. Side effects are known to be related to ocular (keratosis), skin (photosensitivity and pigmentation), thyroid ( Hyperthyroidism or hypothyroidism), neuro-muscle, kidney and lung (fibrosis), etc. Toxicity to the liver has been reported since 1981, most of them are mild changes in liver function, and a few reported acute or chronic liver disease. Hyperlipidemia is caused by many other medications that occur soon after treatment: 1. More common, accounting for about 11-55% of patients taking drugs; 2. All are mild changes in liver function,