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[目的]探讨车间空气中TNT浓度在1.0mg/m3以下时对作业工人肝胆脾、心脏和血压的危害。[方法]对385名接触TNT的作业工人和不接触任何毒物的职工127名进行肝胆脾B超、心电图和血压检查。[结果]肝胆脾B超阳性率TNT组为31.95%,高于对照组的11.02%,差异有统计学意义(P﹤0.01)。肝主要以肿大为主,其次为脂肪肝。肝肿大主要是左肝长径、厚径和右肝斜径增大,脾肿大主要是肋间厚径;肝脾肿大TNT组与对照组比较差异有统计学意义(P﹤0.01)。心电图异常率TNT组为27.27%,高于对照组11.81%,差异有统计学意义(P﹤0.01)。心电图异常类型以窦性心动过缓、过速和不齐为主。血压的改变两组间差异无统计学意义(P﹥0.05),但低血压与工龄不同组间差异有统计学意义(P﹤0.01)。[结论]低浓度接触TNT的作业工人可导致肝胆脾患病率增加、心电图异常率增加以及低血压的改变。
[Objective] To investigate the harm to the workers’ hepatobiliary and spleen, heart and blood pressure when the concentration of TNT in the air of the workshop is below 1.0mg / m3. [Method] A total of 385 workers exposed to TNT and 127 workers not exposed to any toxicants were examined for hepatobiliary and splenic B-ultrasound, electrocardiogram and blood pressure. [Results] The positive rate of hepatobiliary and splenic B-positive in TNT group was 31.95%, which was higher than that in control group (11.02%), the difference was statistically significant (P <0.01). The main liver swelling, followed by fatty liver. Liver enlargement is mainly the major diameter of the left liver, thick diameter and right oblique diameter increased, splenomegaly mainly intercostal diameter; hepatosplenomegaly TNT group and the control group, the difference was statistically significant (P <0.01) . The abnormal rate of ECG in TNT group was 27.27%, which was 11.81% higher than that in control group, the difference was statistically significant (P <0.01). Types of abnormal ECG to sinus bradycardia, tachycardia and irregular. There was no significant difference between the two groups in the change of blood pressure (P> 0.05), but the difference between the two groups was statistically significant (P <0.01). [Conclusion] The workers exposed to low concentration of TNT can lead to the increase of the prevalence of hepatobiliary and splenic, the increase of abnormal ECG rate and the change of hypotension.