目的了解中国中老年人群骨量减少症患病危险因素,为骨量减少症的预防和治疗提供依据。方法采用分层多阶段整群抽样方法对中国五大行政区5103例50岁以上男女人群进行骨密度测量和问卷调查,对216个变量进行多因素非条件Logistic回归分析,得出各危险因素比数比值(OR值)。结果筛选出16个影响我国部分地区骨量减少症患病危险因素,其中,年龄因素(OR=1.0591,1.1269)为男女共同危险因素;心脏病史(OR=1.7623)、慢性呼吸系统疾病史(OR=1.7435)、前12个月背疼史(OR=2.1304)等危险因素在男性中出现;甲状腺疾病史(OR=2.7650)、胃病史(OR=1.5427)、家庭人口数多(OR=1.1404)等危险因素在女性中出现。结论我国中老年人男女骨量减少症患病危险因素中有共同的暴露因素,同时,男女之间的主要危险因素及暴露水平又有一定差异。为今后骨量减少症的防治策略提供重要参考数据。 Objective To understand the prevalence of osteopenia in Chinese middle-aged and elderly population and provide evidence for the prevention and treatment of osteopenia. Methods A multi-stage cluster sampling method was used to measure bone mineral density and questionnaire among 5103 male and female aged 50 and above in the five administrative regions of China. Multivariate unconditional logistic regression analysis was performed on 216 variables and odds ratios of risk factors were obtained. (OR value). Results Sixteen risk factors for bone mineral reduction were screened out in some regions in China. Among them, age factors (OR = 1.0591, 1.1269) were common risk factors for men and women; history of heart disease (OR = 1.7623), history of chronic respiratory disease (OR) = 1.7435). The first 12 months of back pain history (OR = 2.1304) and other risk factors occurred in men; a history of thyroid disease (OR = 2.7650), a history of stomach disorders (OR = 1.5427), and a large family size (OR = 1.1404) Other risk factors appear in women. Conclusions There are common exposure factors in the risk factors of osteopenia among men and women in middle-aged and elderly people in China. At the same time, there are certain differences in the major risk factors and exposure levels between men and women. Provide important reference data for future prevention and treatment strategies for osteopenia.