论文部分内容阅读
目的应用替罗非班及血栓抽吸导管对急性心肌梗死(AMI)患者进行急诊冠脉介入治疗(PCI)治疗,探讨其临床疗效及安全性。方法对符合急诊PCI条件的患者63例,随机分为联合组与常规组,比较两组心肌灌注情况及心脏不良事件(MACE)、出血性并发症发生情况。结果与常规组相比,联合组在校正TIMI血流帧数(cTFC)、2h内ST段回落率、无复流现象等疗效评价指标上,均有明显优势(P﹤0.05),联合组在心脏不良事件及出血性并发症发生率等安全性指标方面,则明显低于常规组,差异有统计学意义(P﹤0.01)。结论接受急诊PCI的AMI患者中,联合应用替非罗班及血栓抽吸导管,明显改善患者的心肌再灌注和预后,并且安全可靠,在紧急救治中占有很大的优势和临床实用价值,值得在急救医疗中全面推广使用。
Objective To evaluate the clinical efficacy and safety of tirofiban and thrombus aspiration catheter in patients undergoing emergency coronary intervention (PCI) in patients with acute myocardial infarction (AMI). Methods Sixty-three patients who met the emergency PCI were randomly divided into combined group and conventional group. The myocardial perfusion and MACE and the incidence of hemorrhagic complications were compared between the two groups. Results Compared with the conventional group, the combined group had obvious advantages in the evaluation of curative effect such as TIMI flow frame number (cTFC), ST-segment resolution within 2 hours and no-reflow phenomenon (P <0.05) Cardiac adverse events and hemorrhagic complications such as safety indicators, was significantly lower than the conventional group, the difference was statistically significant (P <0.01). Conclusions In the AMI patients receiving emergency PCI, the combined application of felodipine and thrombus aspiration catheters significantly improves myocardial reperfusion and prognosis in patients with AMI and is safe and reliable, which has great advantages and clinical practical value in emergency treatment. It is worthwhile In the emergency medical comprehensive promotion.