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为更全面地了解喉癌局部细胞免疫状况，收集14例喉高分化浸润性鳞状细胞癌病例，用其冰冻切片进行了免疫组织化学染色，以CD3（T3／T总淋巴细胞）、CD4（T4／辅助性T淋巴细胞）、CD8（T8／抑制性T淋巴细胞）、CD(22)（B淋巴细胞）及CD(68)（吞噬细胞）抗体，标记了五种免疫细胞。结果喉癌局部浸润的免疫细胞主要为T淋巴细胞，其中以CD3为最多，其次为CD8和CD4细胞，两者中CD8较CD4为多，CD(22)阳性细胞相对少见，CD(68)阳性细胞最少。据此认为喉癌局部主要是T淋巴细胞，尤其是CD8细胞介导的弱细胞毒排斥反应，过继免疫疗法应能使喉癌的局部免疫反应增强。
To know more about the local cellular immunity of laryngeal carcinoma, 14 cases of laryngeal squamous cell carcinoma of the larynx were collected and immunohistochemically stained with frozen section. CD3 (T3 / T total lymphocytes) and CD4 T4 / T helper lymphocytes), CD8 (T8 / suppressor T lymphocytes), CD (22) (B lymphocytes) and CD (68) (phagocyte) antibodies. Results T lymphocytes were predominantly infiltrated by laryngeal cancer, of which CD3 was the most common, followed by CD8 and CD4. CD8 was more abundant than CD4, while CD (22) positive cells were relatively rare and CD (68) positive The least cells. Therefore, it is considered that local laryngeal cancer is mainly T lymphocytes, especially CD8 cell-mediated weak cytotoxicity rejection, and adoptive immunotherapy should enhance the local immune response of laryngeal cancer.