论文部分内容阅读
目的进行保尔佳高浓度介入动脉灌注＋常规化疗方案治疗中晚期胃癌疗效观察。方法30例随机分为治疗组和对照组，各15例；两组治疗均用PDD＋THP＋SFU法，同时治疗组用保尔住每次动脉灌注10ug，术后口服保尔佳片剂100ug,3次用，连续用10天。结果治疗组CR2例，SD2例，PR8例，有效率（CR＋PR）为66．7％，稳定率（PR＋CR＋SD）为93．3％，对照组CR2例，PR7例，有效率（CR＋PR）为466％，稳定率为60％。结果显示治疗组瘤体（包括肝转移）变化明显高于对照组。统计学有显著意义。结论保尔佳高浓度＋常规化疗方案介入灌注化疗，治疗组起到了很好的协同和互补作用，提高了灌注化疗药物的疗效，而且降低了毒副作用，明显改善生活质量，不失为一种介入治疗中有效的药物，值得我们进一步探讨。
Objective To observe the curative effect of Paul good high concentration interventional arterial infusion + conventional chemotherapy in the treatment of advanced gastric cancer. Methods Thirty patients were randomly divided into treatment group (n = 15) and control group (n = 15). PDD + THP + SFU was used in both groups. At the same time, , For 10 consecutive days. Results In the treatment group, the CR2, SD2 and PR8 cases had a CR + PR of 66.7% and a PR (CR + PR) of 93.3%. CR2 and CR7 in the control group were 466% , The stability rate of 60%. The results showed that the treatment group tumor (including liver metastasis) was significantly higher than the control group. Statistics have significant meaning. Conclusions Pallier high concentration + conventional chemotherapy intervention chemotherapy, the treatment group has played a very good synergistic and complementary role, improve the efficacy of perfusion chemotherapy drugs, but also reduce the side effects, and significantly improve the quality of life, after all, an interventional therapy Effective in the drug, we deserve further discussion.