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本文对进展期胃癌并有肝转移41例(下称 HM 组)与无肝转移者35例(NHM)的 X 线和选择性动脉造影表现以及动脉灌注化疗(TAIC)的疗效作了比较,旨在了解原病灶与肝转移的联系以及TAIC 的价值。每例均行 CAG,贲门癌灌注动脉多取 LGA+CA,胃体窦癌为 CHA 或 CA,也可为 LGA,用药绝大多数为 FDM(5FU+CDDP+MMC)。结果表明 HM 组胃癌病变范围≥一个胃分区者和胃重中度变形者明显多于 NHM 组(P<0.005),淋巴结增大浓染和胃壁浆膜浸润率也较 NHM 组高(P<0.005)。全部 CR+PR 率为62.5%,平均生存期8.98个月,半年、1年生存率为61.7%和31.7%,而 HM组平均生存期,CR+PR 率,生存率则明显低于 NHM 组,半年内死亡率显著高于后者(P<0.01)。据此作者强调了 X 线检查的价值,HM 组疗效低与原发病灶广泛、扩散广,临床表现重有关。并对如何改进疗效作了讨论。
This article compared the efficacy of X-ray, selective angiography, and arterial infusion chemotherapy (TAIC) in 41 patients with advanced gastric cancer and liver metastases (hereinafter called HM group) and 35 patients without liver metastases (NHM). In understanding the connection between primary lesions and liver metastases and the value of TAIC. CAG was performed in each case. LCA+CA was used in cardiac perfusion of cardia cancer, and CHA or CA in gastric sinus cancer was also used as LGA. FDM (5FU+CDDP+MMC) was the most commonly used drug. The results showed that the range of gastric cancer lesions in HM group was more than one gastric partitioner and moderate to moderate gastric deformity than in the NNH group (P<0.005), and the lymph node enlargement and the gastric wall serosal infiltration rate were also higher than those in the NNH group (P<0.005). ). The overall CR+PR rate was 62.5% and the average survival period was 8.98 months. The half-year and 1-year survival rates were 61.7% and 31.7%. The mean survival time, CR+PR rate, and survival rate were significantly lower in the HM group than in the NNH group. Mortality was significantly higher in the six months than in the latter (P<0.01). Based on this, the author emphasized the value of X-ray examination. The low efficacy of the HM group was related to the extensive primary lesions, wide spread, and severe clinical manifestations. And discuss how to improve the curative effect.