典型的胰岛素依赖型糖尿病(IDDM)起病急骤,胰岛细胞抗体大都阳性,其症状的出现与病情进展常以周为时间计算单位,但临床上部分病人起病缓慢,开始阶段表现酷似非胰岛素依赖型糖尿病(NIDDM),数年后胰岛β—细胞功能丧失,最终演变为IDDM。此组病人,目前称之为缓慢进展性胰岛素依辕型糖尿病(SPIDDM),或晚发IDDM。 The typical onset of insulin-dependent diabetes mellitus (IDDM) is abrupt. Islet cell antibodies are mostly positive. The appearance and progression of the symptoms are often measured in terms of weeks. However, some patients in the clinical stage have a slow onset and behave like a non-insulin dependent Type diabetes mellitus (NIDDM), a few years after islet β-cell loss, eventually evolving into IDDM. This group of patients, now referred to as slowly progressive insulin-dependent diabetes mellitus (SPIDDM), or late-onset IDDM.