论文部分内容阅读
乙型肝炎病毒(HBV)感染后主要引起急性或慢性肝炎,血清学通常以检测HBV的基因产物(HBsAg、HBeAg)和人体对这些基因产物的抗体(抗-HBs、抗-HBe和抗-HBc)应答来确定HBV感染状态。人们在临床实践中对HBV的常规典型模式两对半及其变化规律已有了一定的认识。近年来,临床上又发现了许多非典型乙型肝炎的病例,有的甚至缺乏血清学标志,使得HBV血清学标志物检测结果与临床表现之间出现矛盾。随着分子生物学的发展,PCR技术的应用,对HBV感染后血清学标志与临床的关系才有了进一步的认识。
Hepatitis B virus (HBV) infection mainly causes acute or chronic hepatitis. Serology usually uses the detection of HBV gene products (HBsAg and HBeAg) and the human antibodies to these gene products (anti-HBs, anti-HBe and anti-HBc ) Response to determine the status of HBV infection. People in the clinical practice of HBV conventional typical pattern of two and a half and its variation has been a certain understanding. In recent years, many clinically found cases of atypical hepatitis B, and some even lack of serological markers, making the results between HBV serological markers and clinical manifestations of contradictions. With the development of molecular biology and the application of PCR technology, further understanding of the relationship between serological markers and clinical manifestations after HBV infection has been made.