人们早就认识到,孕妇饮酒对胎儿会产生很多不良后果,严重者可导致“胎儿酒精综合征”。但父亲饮酒对胎儿有何影响,在这方面的认识还很不够。虽有啮齿动物实验表明,雌性动物与给过酒精的雄性动物交配,其胎仔宫内死亡增加、每胎产仔数降低;还有报道,胎仔雄/雌比增大、畸形增加及出生体重下降。但人群流行病学方面,则仅见Little等报道,丈夫在妻子妊娠前大量饮酒,胎儿出生体重降低。为得到更多依据,本文作者对一项儿童保健与发展研究项目的资料做了进一步分析。研究人群为居住在美国旧金山东部海湾地区,在1959年6月～1966年9月间被确诊为妊娠的孕妇,除外死胎、多胎、不合作、失访、男方饮酒资料不全等因素,符合本文作者研究目的 It has long been recognized that pregnant women drinking alcohol will have a lot of adverse consequences on the fetus, severe cases can lead to “fetal alcohol syndrome.” However, the impact of alcohol consumption on the fetus, in this regard is not enough understanding. Although rodent experiments have shown that mating of females to alcohol-fed males increases their intrauterine death in the litter and decreases litter size per litter, it has also been reported that there is an increase in fetal male / female ratio, an increase in deformity, and a decrease in birth weight . However, in terms of population epidemiology, only Little et al reported that her husband consumed a large amount of alcohol before her pregnancy and her birth weight was reduced. To get more evidence, the author of this paper further analyzed the data of a research project on child health and development. The study population, who lived in the eastern Gulf of San Francisco of the United States between June 1959 and September 1966, was diagnosed as a pregnant woman with the exception of stillbirth, multiple births, non-cooperation, loss of follow-up and incomplete drinking of the man. Research purposes