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目的:探讨对37例多发性骨髓瘤患者进行临床诊断的方法。方法 :对2010年9月~2013年9月期间我院收治的37例多发性骨髓瘤患者的临床资料进行回顾性研究。对这37例患者均进行实验室病理学检查和影像学检查。然后,观察这些患者进行病理学检查和影像学检查的结果。结果 :这37例患者的红细胞值、血红蛋白值、尿酸值、总蛋白值、免疫球蛋白G值、尿蛋白值等各项指标的异常率均在50%以上,其中血沉值的异常率为100%。这37例患者骨髓细胞增生的程度明显活跃,其骨髓瘤细胞的比例在20%~29%之间,其淋巴细胞的数量减少。在进行骨显像检查的27例患者中,有18例患者存在骨折的情况,有7例患者的骨代谢异常活跃,有2例患者发生溶骨性损害。进行MRI影像检查的13例患者均显示出异常信号增强。对23例肺炎患者进行CT扫描诊断的结果,与使用其他检查方法进行肺炎诊断的结果一致。结论 :对多发性骨髓瘤患者可通过实验室病理学检查和影像学检查进行诊断,且诊断的准确性较高。
Objective: To investigate the clinical diagnosis of 37 patients with multiple myeloma. Methods: The clinical data of 37 patients with multiple myeloma treated in our hospital from September 2010 to September 2013 were analyzed retrospectively. All 37 patients underwent laboratory pathology and imaging studies. Then, these patients were observed for pathological examination and imaging findings. Results: The abnormal rates of erythrocyte value, hemoglobin value, uric acid value, total protein value, immunoglobulin G value and urinary protein value in these 37 patients were above 50%, and the abnormal rate of erythrocyte sedimentation rate was 100 %. The degree of myeloid cell hyperplasia in these 37 patients was obviously active. The proportion of myeloma cells was between 20% and 29%, and the number of lymphocytes was decreased. Of the 27 patients who underwent bone imaging, there were 18 patients with fractures, 7 patients had abnormal bone metabolism, and 2 patients had osteolytic lesions. Thirteen patients undergoing MRI imaging showed abnormal signal enhancement. The results of CT scan diagnosis of 23 patients with pneumonia were consistent with the results of pneumonia diagnosis using other examination methods. Conclusion: Multiple myeloma patients can be diagnosed by laboratory pathology and imaging examination, and the diagnostic accuracy is high.