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目前,精神神经免疫学(PNI)研究的最新方向是研究心身之间具有衡量指标的相互作用,尤其是对精神意识、中枢神经系统、机体抗御外来影响及细胞分裂免疫学之间错综复杂的相互作用的研究。它的观点与传统的身心分离观念相对立,但它的基本信念,即早已存在。从历史上来看,人们对身心之间的联系很早就有了科学的认识。例如著名的美国医生James Paget 1870年在《外科病理学》上谈到:“重度焦虑,缺乏信心,失望;很快伴之而来的便是癌症的生长发展,这类病例很常见。对此,我们几乎毫无疑问地讲,精神抑郁是促进癌症发展的一个重要因素”。PNI的早期研究和对精神内分泌通道的认识有关。Cannon关于“战或逃”反应的研究及Selye关于一般适应综合症的研究.在过去30年形成PNI研究的基础,而近10年由于免疫学的迅速发展,揭示了精神因素对健康的影响,使PNI得以充实及发展。
At present, the latest direction of PNI research is the study of interactions between mind and body with metrics, especially the intricate interactions between mental consciousness, the central nervous system, the body’s resistance to external influences, and cell division immunology. Research. Its viewpoint is opposed to the traditional concept of separation of mind and body, but its basic belief is that it already exists. Historically, people have long had a scientific understanding of the connection between body and mind. For example, the famous American doctor James Paget talked about “Surgical Pathology” in 1870: “Severe anxiety, lack of confidence, and disappointment; the rapid development is accompanied by the development of cancer. Such cases are very common. We almost no doubt say that mental depression is an important factor in the development of cancer.” Early studies of PNI were related to the understanding of the psychoendocrine pathway. Cannon’s research on the “war or flight” response and Selye’s research on general adaptation syndrome have formed the basis of PNI research in the past 30 years, and the rapid development of immunology in the past 10 years has revealed the impact of mental factors on health. Make PNI enrich and develop.