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在大鼠失血性休克模型上,观察了重组杀菌/通透性增加蛋白(BPI)对肺组织肿瘤坏死因子(TNF)、白介素-6(IL-6)mRNA表达及急性肺损伤的影响,并对肠源性内毒素血症与炎症细胞因子诱发的关系进行了据讨。 结果显示,失血性休克可导致血浆内毒素
Effects of recombinant bactericidal / permeability-increasing protein (BPI) on the expression of tumor necrosis factor (TNF), interleukin-6 (IL-6) mRNA and acute lung injury in the rat model of hemorrhagic shock were observed The relationship between enterogenous endotoxemia and inflammatory cytokines was discussed. The results show that hemorrhagic shock can lead to plasma endotoxin