论文部分内容阅读
目的:评价盐酸伊托必利片对餐后不适综合征患者胃电活动和胃排空率的影响。方法:将HP检测阴性的42例餐后不适综合征患者随机分为治疗组(铝碳酸镁片+伊托必利片)22例和对照组(铝碳酸镁片)20例,疗程均为4周,治疗前后分别检查胃电图、胃排空率,比较两组各指标的改变有无差异。结果:治疗组:餐后/餐前功率比、反应面积较治疗前显著提高(P<0.05),胃电节律紊乱百分比治疗前后差异无统计学意义(P=0.07);胃排空率较治疗前显著提高(P<0.05)。对照组:治疗前后餐后/餐前功率比、反应面积、胃电节律紊乱百分比差异无统计学意义;胃排空率治疗前后比较差异无统计学意义。结论:伊托必利能显著提高餐后不适综合征患者的胃排空率、餐后/餐前功率比、反应面积,对餐后不适综合征患者有较好的治疗作用。
Objective: To evaluate the influence of itopride hydrochloride tablets on gastric electrical activity and gastric emptying rate in patients with post-prandial discomfort syndrome. Methods: Forty-two patients with post-nausea syndrome with negative HP test were randomly divided into treatment group (aluminum magnesium carbonate tablets + itopride tablets) and control group (aluminum magnesium carbonate tablets) Week, before and after treatment, respectively, check the electrogastrogram, gastric emptying rate, compare the two groups of indicators of any change. Results: In the treatment group, the ratio of postprandial power and reaction area was significantly increased (P <0.05), and the percentage of gastric dysrhythmia was not significantly different before and after treatment (P = 0.07) Before significant increase (P <0.05). In the control group, there was no significant difference in the percentage of postprandial meal / meal power ratio, reaction area and gastric electrical rhythm disturbance before and after treatment. There was no significant difference in the rate of gastric emptying before and after treatment. Conclusion: Itopride can significantly improve the gastric emptying rate, postprandial power ratio and reaction area of patients with post-prandial discomfort syndrome, and has a good therapeutic effect on patients with post-prandial discomfort syndrome.