Diagnostic Indicators for Blood Stasis Syndrome Patients with Gynaecological Diseases

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Objective:To investigate the important diagnostic indicators for blood stasis syndrome (BSS) in patients of childbearing age with gynaecological diseases.Methods:A partial least squared-discriminant analysis (PLS-DA) were applied to BSS symptoms data of patients with gynaecological diseases,and the diagnostic indicators used by doctors of Korean medicine (DKMs) among BSS patients with gynaecological diseases were also investigated.Results:A total of 103 patients of childbearing age with gynaecological diseases and 40 healthy controls were enrolled.Among the 103 patients,63 (61.7%) and 40 (38.8%) were diagnosed with BSS and non-BSS,respectively,and BSS patients exhibited a more severe extent of disease.A score plot of PLS-DA showed clearly different patterns among the 3 groups.Based on the variable importance on projection of PLS-DA model,menstrual pains,dark lumps in the menstrual blood,ileocoecal tenderness and resistance,sharp pains,and sublingual varicosities were selected as the top five most important indicators.Moreover,more than 75% of DKMs chose dark lumps in menstrual blood,menstrual pain,and dark menstrual blood as the diagnostic indicators of BSS in patients with gynaecologicai diseases,and more than 49% of them also considered sharp pains,dark red tongue,sublingual varicosities,and tendency to bruise easily as diagnostic indicators of BSS.Conclusion:DKMs focused on menstrual symptoms and certain gynaecological symptoms to diagnose BSS patients of childbearing age with female diseases.
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