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目的探讨婴儿自发性颅内出血的病因及诊疗方法的选择。方法婴儿自发性颅内出血21例,根据临床特点,经凝血因子、脑脊液、CT、MRI(含MRA)和脑血管造影检查以明确病因诊断。18例为血液病,1例脑动静脉畸形,2例原因不明;手术12例。结果痊愈17例(81%),好转3例(14.3%),死亡1例(4.7%),20例随访1~6年,仅3例肢体轻瘫,2例癫病,CT示5例局灶性脑软化。结论婴儿自发性颅内出血最常见病因系维生素K缺乏症(81%),其次为AVM。及时正确诊治,预后良好。而小骨瓣开颅手术无并发症,疗效好。
Objective To explore the etiology and treatment of spontaneous intracranial hemorrhage in infants. Methods 21 cases of spontaneous intracranial hemorrhage in infants, according to clinical features, clotting factors, cerebrospinal fluid, CT, MRI (including MRA) and cerebral angiography to confirm the etiological diagnosis. 18 cases of hematological diseases, 1 case of cerebral arteriovenous malformations, 2 cases of unknown cause; surgery in 12 cases. The results were cured in 17 cases (81%), improvement in 3 cases (14.3%), death in 1 case (4.7%), 20 cases were followed up 1 to 6 years, only 3 cases of limb paresis, 2 cases of epilepsy, CT showed 5 Cases of focal brain softening. Conclusions The most common cause of spontaneous intracranial hemorrhage in infants is vitamin K deficiency (81%), followed by AVM. Timely diagnosis and treatment, the prognosis is good. The craniotomy craniotomy without complications, good effect.