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目的了解医院住院患者假丝酵母菌属感染的耐药性及流行趋势,为感染预防与控制提供依据。方法收集2012年1月-2014年12月医院所有无菌体液标本分离的假丝酵母菌属,统计医院感染假丝酵母菌属分类构成、阳性检出标本在各科室的分布,并采用ATB FUNGUS药敏试剂条测定药物敏感性。结果 3年共收集假丝酵母菌属454株,其中白色假丝酵母菌196株占43.2%,热带假丝酵母菌106株占23.4%,光滑假丝酵母菌74株占16.3%,近平滑假丝酵母菌54株占11.9%,克柔假丝酵母菌15株占3.3%;无菌体液感染假丝酵母菌属主要从尿液标本中检出,共352株占77.5%,血液检出26株占5.7%,导管远端检出23株占5.1%,分泌物20株占4.4%,引流液15株占3.3%;假丝酵母菌属感染高发科室以ICU、干部病房、肾脏病科等为主。结论假丝酵母菌属感染日益增多应引起高度重视,需制定相应的预防及控制措施,有效降低假丝酵母菌属的感染。
Objective To understand the drug resistance and epidemiological trend of Candida infections in hospitalized patients and provide basis for prevention and control of infection. Methods The Candida species isolated from all the sterile samples of body fluid collected from January 2012 to December 2014 in our hospital were collected and classified into Candida species of hospital infection. The positive samples were distributed in different departments and examined by ATB FUNGUS Drug sensitivity test strips determine drug sensitivity. Results A total of 454 Candida species were collected in 3 years, of which 96 strains accounted for 43.2% of Candida albicans, 106 strains of Candida tropicalis accounted for 23.4%, 74 strains of Candida glabrata accounted for 16.3% 54 strains of filamentous yeast accounted for 11.9% and 15 strains of candida candida accounted for 3.3%. Candida genus was detected mainly from urine samples, accounting for 77.5% of total 352 strains and 26 Strains accounted for 5.7%, 23 were detected distal to the catheter 5.1%, secretions of 20 strains accounted for 4.4%, drainage fluid 15 strains accounted for 3.3%; Candida infections in high incidence of ICU, cadre ward, Department of Nephrology Mainly. Conclusion The increasing incidence of Candida infections should be given high priority. The corresponding prevention and control measures need to be formulated to effectively reduce Candida infections.