三唑类药物具有抗菌活性高，毒副作用少和优越的药代动力学特性。针对伊曲康唑具有较氟康唑更广的抗真菌谱，而氟康唑眼局部应用通透性良好的特点，将这二种三唑类药物联合应用于１５例真菌性角膜溃疡的治疗，其中１４例（９３３％）在治疗１０～２８天内痊愈；而未用三唑类药物治疗的１１例仅６例（５４５％）在治疗１６～７０天内痊愈。两组比较治愈率及疗程均有显著性差异（Ｐ＜００５，Ｐ＜００１）。联合治疗的费用较低，应用方便，疗效可靠。 Triazole drugs with high antibacterial activity, fewer side effects and superior pharmacokinetic properties. In view of the fact that itraconazole has a broader antifungal spectrum than fluconazole and the topical fluconazole eye has good permeability, the two triazole drugs are used in combination with 15 cases of fungal corneal ulcer Among them, 14 (933%) recovered within 10 to 28 days of treatment, while only 6 (545%) of 11 patients without triazole were cured within 16 to 70 days after treatment. There was significant difference between the two groups in cure rate and treatment (P <005, P <001). The cost of combination therapy is lower, the application is convenient and the curative effect is reliable.