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目的比较早期与择期介入治疗对高危非ST段抬高型心肌梗死(NSTEMI)患者短期预后的影响。方法纳入西京医院心血管内科行介入治疗的高危NSTEMI患者,根据手术实施时间分为早期介入组(入院24 h内)和择期介入组(24~48 h)。比较两组患者围手术期并发症、住院期间死亡、PCI成功率、住院时间以及费用,对患者随访6个月,观察再发心绞痛、因冠心病再住院、主要心血管不良事件(MACE)的发生和左心室射血分数(LVEF)改善的情况。结果与择期介入组比较,早期介入组围手术期并发症、住院期间死亡、PCI成功率与MACE发生率差异无统计学意义,早期介入组住院时间、住院费用、再发心绞痛及因冠心病再住院率低于择期介入组,两组LVEF均明显提高,早期介入组高于择期介入组。结论高危NSTEMI患者早期介入治疗的短期预后优于择期介入治疗。
Objective To compare the short-term prognosis of patients with high-risk non-ST-segment elevation myocardial infarction (NSTEMI) treated with early and selective interventional therapy. Methods Patients with high-risk NSTEMI undergoing interventional intervention in Xijing Hospital were divided into early intervention group (24 h) and elective intervention group (24-48 h) according to the time of operation. Perioperative complications, death during hospitalization, PCI success rate, hospitalization time and cost were compared between the two groups. The patients were followed up for 6 months. Recurrence of angina pectoris, re-admission due to coronary heart disease, major adverse cardiovascular events (MACE) Occurred and left ventricular ejection fraction (LVEF) improved. Results Compared with the elective intervention group, there was no significant difference in perioperative complications, death during hospitalization, PCI success rate and MACE incidence in the early intervention group. There was no significant difference in the incidence of hospitalization, hospitalization, angina pectoris and coronary heart disease The hospitalization rate was lower than that of the elective intervention group, and the LVEF of both groups was significantly higher than that of the elective intervention group. Conclusion Early intervention in high-risk NSTEMI patients is better than elective intervention in short-term prognosis.