[病例229] 患者50岁,家庭妇女,初诊于1979年8月10日。病历:患者27岁结婚。从事洗涤工作以来指甲干燥、粗糙,发红,不久手掌全部发红、干燥、硬化、瘙痒。一抓就破而不能见水。后来口唇也粗糙起来,并扩展到全身皮肤,尤其是上半身。脸也全部粗糙起来,发痒。胸全部、两边胳膊也像洒白粉那样粗糙起来。 [Case 229] The patient was 50 years old and was a family member. He was first diagnosed on August 10, 1979. Medical records: The patient married at 27 years old. The nails are dry, rough and red since washing, and soon the palms are all red, dry, hardened, and itchy. A scratch can not see the water. Later, the lips were rough and extended to the skin, especially the upper body. The face is all rough and itchy. All the chest and arms on both sides are as rough as white powder.