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银杏叶提取物(EGb 761)药理成分丰富,目前已在其中发现200多种化合物,其中含量较高的为黄酮和内脂,银杏叶提取物广泛应用于心脑血管疾病和神经系统疾病的防治,近年来研究发现银杏叶提取物对一些肿瘤也有一定的抑制作用。体外研究显示银杏叶提取物及其组分可抑制胰腺癌细胞MIA PaCa-2及Panc-1〔1〕、人结肠癌细胞HT-29〔2〕、乳腺癌细胞MDA-231〔3〕及MCF-7〔4〕增殖,体内研究报导银杏叶提取物及其组分可明显遏制动物诱发性肝癌增
Ginkgo biloba extract (EGb 761) rich in pharmacological components, has been found in more than 200 kinds of compounds, of which the higher content of flavonoids and lactone, Ginkgo biloba extract is widely used in the prevention and treatment of cardiovascular and cerebrovascular diseases and nervous system diseases In recent years, studies have found that some extracts of Ginkgo biloba also have some inhibitory effect. In vitro studies have shown that Ginkgo biloba extract and its components can inhibit pancreatic cancer cells MIA PaCa-2 and Panc-1 [1], human colon cancer cells HT-29 〔2〕, breast cancer cells MDA-231 〔3〕 and MCF -7 〔4〕 proliferation, in vivo studies have reported Ginkgo biloba extract and its components can significantly inhibit animal induced liver cancer by