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肾上腺皮质癌极罕见,发病率约1:170万,1~10岁和41~50岁两年龄段患病高峰年龄中位数分别为4及44岁,60%~70%见于女性。本文报道1例肾上腺皮质癌术后辅助化疗后获妊娠且无复发。 患者24岁,痤疮、多毛加重1年,原发不孕2年,月经规则,体查:BMI25.3,面部多发痤疮,全身多毛,阴毛呈男性分布,阴蒂肥大,血清睾酮(T)、去氢表雄酮硫酸盐(DS)、游离T、17α-羟孕酮均增高各
Adrenocortical carcinoma is extremely rare, with an incidence of approximately 1:1.7 million. The median age at peak ages of 1 to 10 and 41 to 50 years of age are 4 and 44 years respectively, and 60% to 70% of them are found in women. This article reports one case of adrenocortical carcinoma with postoperative adjuvant chemotherapy and no recurrence. The patient was 24 years old and had acne and hairyness that had worsened for 1 year, primary infertility for 2 years, menstrual rules, physical examination: BMI 25.3, multiple facial acne, hairy body, male pubic hair distribution, clitoral hypertrophy, serum testosterone (T), go Hydrogenosterone sulfate (DS), free T, and 17α-hydroxyprogesterone all increased