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乙肝相关性肾炎是一种临床诊断及治疗均较为困难的疾病,目前现代医学对乙肝相关性肾炎的治疗尚缺乏低毒高效的药物,主要是采用免疫抑制、抗病毒和对症治疗。但免疫抑制剂可能促进乙肝病毒复制而加重肝脏病变,抗病毒药物或有一定肾毒性,单用并不能完全控制肾脏病变,故在乙肝相关性肾炎治疗中自相矛盾且往往疗效不佳。本文从脾肾立论,从病因病机、治则治法、预防调护三方面阐述乙肝相关性肾炎与脾肾的关系,为临床治疗乙肝相关性肾炎提供思路,也为临床治疗乙肝相关性肾炎提供参考。
Hepatitis B-related nephritis is a clinical diagnosis and treatment of more difficult diseases, the current medical treatment of hepatitis B-related nephritis is still lack of low-toxic drugs, mainly immunosuppressive, anti-virus and symptomatic treatment. However, immunosuppressive agents may promote hepatitis B virus replication and aggravate liver disease, antiviral drugs or have some nephrotoxicity, alone and can not completely control the renal disease, it is self-contradictory and often ineffective in the treatment of hepatitis B-related nephritis. This article from the spleen and kidney standpoint, from the etiology and pathogenesis, rule the rule of law, prevention and treatment of three aspects of hepatitis B-related nephritis and spleen and kidney relations for the treatment of hepatitis B-related nephritis provides ideas for the clinical treatment of hepatitis B-related nephritis provide reference.