论文部分内容阅读
自50年代开始采用肾上腺皮质激素类药物治疗红斑性狼疮以来,狼疮肾炎的预后已发生改观。虽然目前尚无根治狼疮肾炎的方法,治疗药物仍以皮质激素类为主,也酌情联用免疫抑制剂、非激素类抗炎药、抗凝剂、抗血小板制剂、免疫兴奋剂等,但已积累了针对临床表现与组织学改变等而制订治疗措施的用药经验。本文根据文献资料,对狼疮肾炎的治疗近况,包括主要治疗药物及其作用机理、治疗原则、不同类型狼疮肾炎的治疗方案、激素脉冲疗法、血浆交换疗法以及妊娠时狼疮肾炎的治疗等,作一简述,供参考.
The prognosis for lupus nephritis has changed since the advent of corticosteroids in the treatment of lupus erythematosus since the 1950s. Although there is no cure for lupus nephritis, the therapeutic drugs are still mainly corticosteroids, but also with immunosuppressive agents, non-hormone anti-inflammatory drugs, anticoagulants, antiplatelet agents, immune stimulants, etc., Accumulation of clinical manifestations and histological changes in the formulation of treatment measures of drug experience. This article based on the literature, the status of treatment of lupus nephritis, including the main therapeutic agents and their mechanism of action, the principle of treatment, different types of treatment of lupus nephritis, hormone pulse therapy, plasma exchange therapy and treatment of lupus nephritis during pregnancy, for a Briefly, for reference.