大鼠腹腔肥大细胞,是供过敏反应的体外试验、研究药物抗原性(过敏原性)和筛选抗过敏药物等的良好模型。其分离纯化多采用Ficoll。本文介绍用阿拉伯树胶的分离方法分离后纯度97±0.93％;回收率59±7.8％;自然脱颗粒细胞少于10％;对抗原仍保持良好反应能力。此外,介绍了一个在筛选药物中初步应用的例子。 Rat peritoneal mast cells, is an in vitro test for allergic reactions, a good model for the study of drug antigenicity (allergenicity) and screening anti-allergy drugs. The separation and purification to use more Ficoll. This article describes the use of gum arabic separation purity of 97 ± 0.93%; recovery of 59 ± 7.8%; natural degranulation less than 10%; still maintain a good response to the antigen. In addition, an example of the initial application in screening drugs is presented.