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目的评估中西医结合治疗精液液化异常的效果。方法将230例精液液化异常症患者随机分成两组,中西医结合治疗组(简称治疗组)和西医治疗组(简称对照组)各115例。对照组给予克拉霉素分散片、盐酸坦索罗辛缓释胶囊和葡萄糖酸锌口服,治疗组在对照组基础上加用自拟促液化汤,1剂/d,分2次早晚服用。观察两组治疗前后精液、前列腺液主要参数的变化以及精浆前列腺特异性抗原、酸性磷酸酶、柠檬酸和锌的含量。结果治疗组有效率为94.8%,对照组有效率为71.3%,两组疗效比较差异有统计学意义(P<0.01)。治疗后治疗组精子密度、活率;前列腺液中的卵磷脂小体、白细胞数目以及精浆有关生化指标的改善优于对照组(P<0.01)。结论应用中西医结合疗法治疗精液不液化,较单纯用西药治疗效果良好,其在提高精液质量、改善前列腺功能方面显著优于对照组。
Objective To evaluate the effect of combining traditional Chinese and western medicine on the abnormal liquefaction of semen. Methods A total of 230 patients with semen liquefaction disorders were randomly divided into two groups: 115 cases in Integrative Medicine Group (referred to as treatment group) and Western Medicine Treatment Group (abbreviated as control group). Control group was given clarithromycin dispersible tablets, tamsulosin hydrochloride sustained release capsules and oral zinc gluconate, the treatment group in the control group based on the addition of self-promoting liquid soup, 1 / d, 2 times morning and evening taking. The changes of the main parameters of semen and prostatic fluid before and after treatment and the contents of prostate specific antigen, acid phosphatase, citric acid and zinc in seminal plasma were observed. Results The effective rate was 94.8% in the treatment group and 71.3% in the control group, with significant difference between the two groups (P <0.01). After treatment, the sperm density and viability of the treatment group were better than those of the control group (P <0.01). The lecithin body, the number of white blood cells in the prostatic fluid and the biochemical indexes in the seminal plasma were better than those in the control group. Conclusion The combination of TCM and Western medicine treatment of semen liquefaction, compared with simple Western medicine treatment effect is good, which improve sperm quality, improve prostate function was significantly better than the control group.