论文部分内容阅读
目的探讨布地奈德雾化吸入治疗急性毛细支气管炎的临床疗效。方法将2010年4月-2012年4月就诊于安徽广德县人民医院儿科80例急性毛细支气管炎患儿随机分为观察组与对照组,各40例。两组患儿均常规给予吸氧、祛痰、抗病毒等对症治疗,观察组在常规治疗基础上加用布地奈德雾化溶液0.5 mg雾化吸入,每天2次,疗程7 d。观察两组患儿在治疗后喘憋、咳嗽、肺部哮鸣音及湿啰音消失所需的时间、住院时间和不良反应的情况。结果比较两组患儿的治疗有效率,观察组有效率达95%,对照组为80%,两组之间差异具有统计学意义(P<0.05);比较两组患儿喘憋、哮鸣音、湿啰音和咳嗽消失时间及住院时间,观察组各观察指标均显著短于对照组,差异亦具有统计学意义(P<0.05);治疗过程中两组患儿均未出现明显不良反应。结论布地奈德雾化溶液雾化吸入治疗急性毛细支气管炎能明显改善患儿临床症状,缩短住院时间,具有疗效确切、安全性好等优点。
Objective To investigate the clinical efficacy of inhaled budesonide in the treatment of acute bronchiolitis. Methods From April 2010 to April 2012, 80 children with acute bronchiolitis admitted to Guangde County People’s Hospital of Anhui Province were randomly divided into observation group and control group, 40 cases in each group. Two groups of children were routinely given oxygen, expectorant, antiviral and other symptomatic treatment, the observation group on the basis of conventional treatment plus budesonide atomization solution 0.5 mg inhalation, 2 times a day for 7 days. Observe the two groups of children in the treatment of wheezing, cough, lung wheeze and wet rales the disappearance of time, length of stay and adverse reactions. Results The effective rate of treatment in both groups was 95% in the observation group and 80% in the control group, with significant difference between the two groups (P <0.05). The wheezing and wheezing were compared between the two groups (P <0.05). There was no significant adverse reaction in both groups in the course of treatment . Conclusion The inhalation of budesonide atomized solution for the treatment of acute bronchiolitis can significantly improve the clinical symptoms and shorten the length of hospital stay, with the advantages of good curative effect and good safety.