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目的探讨常规开胸与胸腔镜下治疗早期胸腺瘤患者的临床效果。方法选取2013年1月至2015年1月沈阳军区总医院收治的84例早期胸腺瘤患者作为研究对象,采用随机数字表法将其分为对照组和观察组,各42例。对照组患者给予常规开胸治疗,观察组患者采用胸腔镜下手术进行治疗,比较两组患者术中出血量、手术时间、引流量、住院时间、肺功能、并发症及复发情况。结果观察组患者的术中出血量、引流量均明显少于对照组,手术时间、住院时间均明显短于对照组,差异均有统计学意义(均P<0.05);治疗后,观察组患者的第1秒钟用力呼气容积(FEV1)、用力肺活量(FVC)均明显高于对照组,疲劳指数明显低于对照组,差异均有统计学意义(均P<0.05);观察组患者的并发症发生率明显低于对照组,差异有统计学意义(χ~2=3.896,P<0.05)。结论胸腔镜下手术治疗胸腺瘤与传统开胸手术相比具有手术创伤小、术中出血量少、患者恢复快的优势,且手术安全性高,对肺功能影响较小。
Objective To investigate the clinical effects of conventional thoracotomy and thoracoscopic treatment of early thymoma patients. Methods Eighty-four patients with early-stage thymoma treated in Shenyang General Hospital of PLA from January 2013 to January 2015 were selected and divided into control group and observation group with 42 cases in each group. Patients in the control group were treated by conventional thoracotomy. Patients in the observation group were treated by thoracoscopic surgery. Blood loss, operation time, drainage, hospital stay, lung function, complications and recurrence were compared between the two groups. Results In the observation group, the intraoperative blood loss and drainage were significantly less than those in the control group, and the operation time and hospitalization time were significantly shorter than those in the control group (all P <0.05). After treatment, the patients in the observation group (FEV1) and forced vital capacity (FVC) were significantly higher than the control group, the fatigue index was significantly lower than the control group, the difference was statistically significant (all P <0.05); the observation group patients Complication rate was significantly lower than the control group, the difference was statistically significant (χ ~ 2 = 3.896, P <0.05). Conclusion Thoracoscopic surgery for thymoma compared with conventional thoracic surgery has the advantages of less surgical trauma, less intraoperative blood loss, faster recovery of patients, and surgical safety, less impact on pulmonary function.