白霉素是临床常用的抗菌素。目前广泛用于革兰阳性球菌,对耐红霉素的金葡菌效力更好,临床主要用于上呼吸道感染、肺炎、胆囊炎、百日咳、扁桃体炎、败血症等。一般认为白霉素在用药方面比其它抗菌素(如青霉素)安全可靠,随着临床应用的日益广泛,发现该药出现副作用例数逐渐增加。根据我科门诊3年来500例的不完全统计,不良反应类型主要为三种:过敏性荨麻疹,胃肠道反应,头痛。讨论:白霉素的抑菌机理是进入机体与核糖蛋白体的50亚单位相结合,抑制肽酰基转移 White Clinic is commonly used in clinical antibiotics. Currently widely used in Gram-positive cocci, erythromycin-resistant Staphylococcus aureus is better, clinical mainly for upper respiratory tract infection, pneumonia, cholecystitis, whooping cough, tonsillitis, sepsis and so on. Generally believed that the white drug in the medication than other antibiotics (such as penicillin) safe and reliable, with the increasingly wide range of clinical applications, found that the drug appears to increase the number of cases of side effects. According to the incomplete statistics of 500 cases in our clinic for three years, there are mainly three types of adverse reactions: allergic urticaria, gastrointestinal tract reaction and headache. Discussion: The antibacterial mechanism of leukomycin is to enter the body and ribosomal protein 50 subunit combined to inhibit peptide acyl transfer