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目的介绍山东多中心健康管理纵向观察队列,描述该队列资料的主要变量和疾病的特征,阐明本队列构建的目标。方法山东多中心健康管理纵向观察队列为前瞻性、动态开放式队列。自2004年开始了数据采集、数据库构建、队列随访等一系列工作,迄今队列总人数已近100万人,最长观察时间已达12年,大约20%个体与医疗保险疾病结局数据和死因数据库实现了合并。信息收集包括问卷调查、体格检查和实验室检测。结果本次研究个体数为76 368人,男43 818人,女32 550人。高血压、糖尿病、脑卒中、冠心病的累积发病风险分别为49.40%、23.98%、4.74%和6.82%。结论山东多中心健康管理纵向观察队列是研究各种因素在慢性病发生、发展和转归过程中的作用、构建适用于健康管理人群疾病风险评估模型的基础,基于该队列的各项研究结果能够为慢性病的健康干预提供科学依据。
Objective To introduce Shandong multicentre health management vertical observation cohort, describe the main variables of the cohort data and disease characteristics, and elucidate the goals of this cohort construction. Methods Shandong multicentre health management longitudinal observation cohort was prospective, dynamic and open cohort. Since 2004, a series of work has been carried out on data collection, database construction and follow-up of cohorts. The total number of cohorts has reached nearly 1 million so far and the longest observation time has reached 12 years. About 20% of individuals have data on the outcome of medical insurance and the cause of death database Achieved a merger. Information collection includes questionnaires, physical examination and laboratory tests. Results The study population was 76,368 individuals, 43,818 males and 32,550 females. The cumulative incidence of hypertension, diabetes, stroke and coronary heart disease were 49.40%, 23.98%, 4.74% and 6.82%, respectively. Conclusion Longitudinal observation of multicentre health management in Shandong is to study the role of various factors in the occurrence, development and prognosis of chronic diseases and to build a foundation for the disease risk assessment model of health management population. The results of the studies based on this cohort can be Provide a scientific basis for the health intervention of chronic diseases.