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分泌型免疫球蛋白 (s IgA)是粘膜体液免疫最主要的功能执行者。s IgA的产生过程具有不同于非粘膜部位Ig生成的特点。s IgA在体内具有粘膜结构的表面及外分泌腺等部位 ,通过免疫清除、免疫屏障及中和作用 ,将病原微生物排出体外 ,达到了保护机体之目的。关于神经系统对s IgA的调节 ,虽然资料有限但已见端倪。本文论述的消化道粘膜s IgA免疫的原理及意义普遍适用于体内共同的粘膜免疫系统
Secretory immunoglobulin (s IgA) is the most important functional operator of mucosal humoral immunity. s IgA production process has a different characteristics of non-mucosal Ig formation. s IgA in the body with mucosal surface and exocrine gland and other parts of the body, through immune clearance, immune barrier and the role of neutralization, the pathogenic microorganisms excreted, to protect the body’s purpose. On the nervous system of s IgA regulation, although limited data but has been clues. This article discusses the principle and significance of gastrointestinal mucosal s IgA immunity is generally applicable to the common mucosal immune system in vivo